SCHEMBL31379005

SCHEMBL31379005

O=CC[C@@H](O)c1ccccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 2/20 0.50
ADRB1 P08588 2/20 0.50
AOC3 Q16853 1/20 0.50
HIF1A Q16665 3/20 0.49
CYP2D6 P10635 2/20 0.49
NFKB1 P19838 1/20 0.49
BLM P54132 2/20 0.47
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP1A2 P05177 1/20 0.42
CASP1 P29466 1/20 0.40
ACP3 P15309 1/20 0.40
NISCH Q9Y2I1 1/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TSHR P16473 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28418763 1.00 ADRB2 (0.50) ADRB2ADRB1AOC3HIF1ACYP2D6
SCHEMBL5322206 0.81 ADRB2 (0.50) ADRB2ADRB1AOC3HIF1ACYP2D6
SCHEMBL31257276 0.81 ADRB2 (0.50) ADRB2ADRB1AOC3HIF1ACYP2D6
SCHEMBL31378986 0.78 ADRA2C (0.47) HIF1AKMT2ATDP1ALDH1A1TSHR
SCHEMBL2208943 0.77 ESR1 (0.41) CYP2D6CYP3A4CYP1A2ACP3MEN1
SCHEMBL31378992 0.77 ESR1 (0.41) CYP2D6CYP3A4CYP1A2ACP3MEN1
SCHEMBL17755070 0.77 ADRB2 (0.42) ADRB2ADRB1AOC3HIF1ACYP2D6
SCHEMBL31378978 0.77 CES2 (0.44) CYP2D6CYP3A4CYP2C9MEN1KMT2A
SCHEMBL27688214 0.76 ACP3 (0.46) HIF1ABLMCYP3A4CYP2C9CYP2C19
SCHEMBL3489603 0.75 AOC3 (0.61) ADRB2ADRB1AOC3HIF1ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409676-A Preparation method for synthesizing chiral beta-hydroxy propanal ethylene glycol with high enantioselectivity 贵州金之键高科技材料股份有限公司 2025-02-11 CN disclosed