SCHEMBL31379277

SCHEMBL31379277

COC(=O)[C@@H]1CCCN1S(C)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.54
ANPEP P15144 1/20 0.54
TP53 P04637 1/20 0.51
CASP3 P42574 1/20 0.46
POLB P06746 1/20 0.45
FKBP1A P62942 2/20 0.40
CYP19A1 P11511 1/20 0.39
PEPD P12955 2/20 0.38
XPNPEP1 Q9NQW7 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8005260 1.00 MMP2 (0.54) MMP2ANPEPTP53CASP3POLB
SCHEMBL27509233 1.00 MMP2 (0.54) MMP2ANPEPTP53CASP3POLB
SCHEMBL16382428 0.95 MMP2 (0.53) MMP2ANPEPTP53CASP3POLB
SCHEMBL692909 0.85 CASP3 (0.46) MMP2ANPEPTP53CASP3POLB
SCHEMBL30149224 0.85 CASP3 (0.46) MMP2ANPEPTP53CASP3POLB
SCHEMBL1523018 0.85 CASP3 (0.46) MMP2ANPEPTP53CASP3POLB
SCHEMBL7338741 0.84 CASP3 (0.45) MMP2ANPEPTP53CASP3POLB
SCHEMBL9131956 0.84 CASP3 (0.45) MMP2ANPEPTP53CASP3POLB
SCHEMBL28847883 0.84 CASP3 (0.45) MMP2ANPEPTP53CASP3POLB
SCHEMBL23897220 0.81 CASP3 (0.49) MMP2ANPEPTP53CASP3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743175-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Aconcagua Bio, Inc. (US) 2026-05-20 EP disclosed
US-20250051355-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO, INC. 2025-02-13 US disclosed
WO-2025015269-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO, INC. (US) 2025-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051355-A1 COMPOUNDS, COMPOSITIONS, AND METHODS IAPP, GIPR, GPR119 MMP2 2301/4885ANPEP 563/4885TP53 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.