Fluoride

Fluoride

SCHEMBL31379740

F.Oc1nc2ccccc2[nH]1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ABCB11 O95342 1/20 0.58
TP53 P04637 1/20 0.58
PKM P14618 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HSD17B10 Q99714 1/20 0.58
MASP2 O00187 1/20 0.54
MEN1 O00255 1/20 0.54
NUDT1 P36639 1/20 0.54
KMT2A Q03164 1/20 0.54
AOC3 Q16853 1/20 0.54
IDO1 P14902 1/20 0.53
AURKA O14965 1/20 0.52
JAK2 O60674 1/20 0.52
ABL1 P00519 1/20 0.52
NTRK1 P04629 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75450 0.98 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ANPSR1KDM4E
SCHEMBL29437860 0.98 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ANPSR1KDM4E
SCHEMBL28329057 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ANPSR1KDM4E
SCHEMBL28178955 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ANPSR1KDM4E
Pyrrole SCHEMBL5553963 0.88 NPC1 (0.50) ALDH1A1NPC1RAB9ANPSR1KDM4E
Guanidine SCHEMBL4196964 0.88 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ANPSR1KDM4E
Pyrimidine SCHEMBL5798169 0.86 KDM4E (0.48) ALDH1A1NPC1RAB9ANPSR1KDM4E
SCHEMBL8863098 0.83 FGFR1 (0.46) ALDH1A1NPC1RAB9ANPSR1KDM4E
Acrylic Acid SCHEMBL28407604 0.82 CHRM1 (0.46) ALDH1A1NPC1RAB9ANPSR1KDM4E
SCHEMBL9987456 0.82 DDAH1 (0.54) ALDH1A1NPC1RAB9AKDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025013869-A1 FLUORINE-CONTAINING POLYMER HAVING NITROGEN-CONTAINING AROMATIC RING, PRODUCTION METHOD THEREFOR, AND COMPOSITION THEREOF ダイキン工業株式会社 2025-01-16 WO disclosed