SCHEMBL75450

SCHEMBL75450

Oc1nc2ccccc2[nH]1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
NPSR1 Q6W5P4 2/20 0.60
KDM4E B2RXH2 1/20 0.60
ABCB11 O95342 1/20 0.60
TP53 P04637 1/20 0.60
PKM P14618 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HSD17B10 Q99714 1/20 0.60
MASP2 O00187 1/20 0.56
MEN1 O00255 1/20 0.56
NUDT1 P36639 1/20 0.56
KMT2A Q03164 1/20 0.56
AOC3 Q16853 1/20 0.56
IDO1 P14902 1/20 0.55
AURKA O14965 1/20 0.53
JAK2 O60674 1/20 0.53
ABL1 P00519 1/20 0.53
NTRK1 P04629 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437860 1.00 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ANPSR1KDM4E
Fluoride SCHEMBL31379740 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ANPSR1KDM4E
Pyrrole SCHEMBL5553963 0.90 NPC1 (0.50) ALDH1A1NPC1RAB9ANPSR1KDM4E
Guanidine SCHEMBL4196964 0.90 ALDH1A1 (0.52) ALDH1A1NPC1RAB9ANPSR1KDM4E
Pyrimidine SCHEMBL5798169 0.88 KDM4E (0.48) ALDH1A1NPC1RAB9ANPSR1KDM4E
SCHEMBL8863098 0.85 FGFR1 (0.46) ALDH1A1NPC1RAB9ANPSR1KDM4E
Acrylic Acid SCHEMBL28407604 0.84 CHRM1 (0.46) ALDH1A1NPC1RAB9ANPSR1KDM4E
SCHEMBL9987456 0.84 DDAH1 (0.54) ALDH1A1NPC1RAB9AKDM4ETP53
SCHEMBL11357960 0.76 KDM4E (0.55) ALDH1A1NPC1RAB9AKDM4EPKM
SCHEMBL503219 0.76 ALDH1A1 (0.54) ALDH1A1NPC1RAB9ANPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3829 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2025-05-08 US claimed
CN-118755219-B Acid and alkali resistant fluororubber and preparation method and application thereof 安徽道格思新材料有限公司 2025-04-29 CN claimed
CN-119823635-A High-strength heat-preservation heat-insulation building coating and preparation method thereof 广东东方一哥新材料股份有限公司 2025-04-15 CN claimed
CN-119710839-A Passivation anti-discoloration agent for cyanide-free cadmium plating after high-temperature baking and application thereof 重庆置道科技有限公司 2025-03-28 CN claimed
CN-119462765-A DOPO-HQ-based flame retardant, preparation method and application thereof, flame-retardant anti-dripping PET composite material and preparation thereof 浙江梅盛新材料有限公司 2025-02-18 CN claimed
CN-115282782-B Total heat exchange membrane doped with functionalized ZIF-7 nanoparticles and preparation method thereof 浙江工业大学 2025-01-28 CN claimed
WO-2025013869-A1 FLUORINE-CONTAINING POLYMER HAVING NITROGEN-CONTAINING AROMATIC RING, PRODUCTION METHOD THEREFOR, AND COMPOSITION THEREOF ダイキン工業株式会社 2025-01-16 WO claimed
CN-119285555-A Preparation method of 2-hydroxy benzimidazole 中船(邯郸)派瑞特种气体股份有限公司 2025-01-10 CN claimed
CN-119284909-A Method for improving quick charging performance of silicon-carbon composite material 贵州晖阳科技创新研究有限公司 2025-01-10 CN claimed
CN-119075717-A Polysulfone composite oil-water separation membrane with ZIF-7-OH surface modification, and preparation method and application thereof 浙江工业大学 2024-12-06 CN claimed
EP-0348170-A2 Antiviral pyrimidine derivatives Lee, Moses Nam Fong (CA) 1989-12-27 EP claimed
WO-1988009351-A1 FLAME RETARDANT INTERNALLY CURED POLYURETHANE FOAM HAVING IMPROVED PROPERTIES REEVES BROTHERS, INC. (US) 1988-12-01 WO claimed
EP-0170164-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
US-4757094-A Improved compression set properties REEVES BROTHERS, INC. (US) 1988-07-12 US claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
US-4643793-A WITH MIXTURE OF COPPER COMPOUND, COMPLEXING AGENT, REDUCING AGENT, AND PH ADJUSTER IN PRESENCE OF NITROGEN HETEROCYCLE COMPOUND HITACHI CHEMICAL COMPANY, LTD. (JP) 1987-02-17 US claimed
US-H122-H PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1986-09-02 US claimed
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP claimed
EP-0170414-A2 Process for treating metal surface Hitachi Chemical Co., Ltd. (JP) 1986-02-05 EP claimed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US claimed