SCHEMBL3137976

SCHEMBL3137976

O=S(=O)(c1ccc(SCCO)cc1)c1ccc(SCCO)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 11/20 0.72
CA12 O43570 4/20 0.72
CA1 P00915 4/20 0.72
CA7 P43166 3/20 0.72
CA13 Q8N1Q1 3/20 0.72
ALDH1A1 P00352 5/20 0.41
CYP3A4 P08684 3/20 0.41
TSHR P16473 3/20 0.41
LMNA P02545 2/20 0.41
CYP2C9 P11712 2/20 0.41
MAPK1 P28482 2/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
APAF1 O14727 1/20 0.41
MAP2K7 O14733 1/20 0.41
NPC1 O15118 1/20 0.41
GMNN O75496 1/20 0.41
TDP2 O95551 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811988 0.94 CA2 (0.66) CA2CA12CA1CA7CA13
SCHEMBL3137951 0.89 CA2 (0.59) CA2CA12CA1CA7CA13
SCHEMBL14351561 0.88 CA2 (0.74) CA2CA12CA1CA7CA13
Acrylic Acid SCHEMBL6631376 0.87 CA2 (0.57) CA2CA12CA1CA7CA13
SCHEMBL10532586 0.84 CA2 (1.00) CA2CA12CA1CA7CA13
SCHEMBL811362 0.84 CA2 (0.54) CA2CA12CA1CA7CA13
SCHEMBL811796 0.84 CA2 (0.54) CA2CA12CA1CA7CA13
SCHEMBL8637757 0.82 CA2 (0.61) CA2CA12CA1CA7CA13
SCHEMBL13696518 0.80 CA2 (0.49) CA2CA12CA1CA7CA13
SCHEMBL3139223 0.79 CA2 (0.47) CA2CA12CA1CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663693-A1 METHOD FOR DECOMPOSING COMPOUND National Institute Of Advanced Industrial Science and Technology (JP) 2025-12-17 EP disclosed
WO-2024166919-A1 METHOD FOR DECOMPOSING COMPOUND 国立研究開発法人産業技術総合研究所 2024-08-15 WO disclosed
US-9365507-B2 Diaryl sulfone compound, and manufacturing method for same SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2016-06-14 US disclosed
EP-2548860-A1 NOVEL DIARYL SULFONE COMPOUND, AND MANUFACTURING METHOD FOR SAME Sumitomo Seika Chemicals CO. LTD. (JP) 2013-01-23 EP disclosed
US-20130005982-A1 NOVEL DIARYL SULFONE COMPOUND, AND MANUFACTURING METHOD FOR SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2013-01-03 US disclosed
WO-2011083652-A1 ACTINIC-RADIATION CURABLE COMPOSITION AND USES THEREOF 日本合成化学工業株式会社 (JP) 2011-07-14 WO disclosed
EP-2139878-A2 HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF BASF SE (DE) 2010-01-06 EP disclosed
US-20090220770-A1 POLYMERIZABLE COMPOSITION, HIGH-REFRACTIVE-INDEX RESIN COMPOSITION, AND OPTICAL MEMBER MADE OF THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-03 US disclosed
WO-2008101806-A2 HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF BASF SE (CH) 2008-08-28 WO disclosed
US-20080200582-A1 High refractive index monomers, compositions and uses thereof CIBA CORP. 2008-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130005982-A1 NOVEL DIARYL SULFONE COMPOUND, AND MANUFACTURING METHOD FOR SAME SULT1A1, SULT1E1, SULT2A1 CA2 3589/4885CA12 2809/4885CA1 2431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.