Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 5/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.51 |
| ▸ | JAK2 | O60674 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | IDH2 | P48735 | 6/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31379936 | 0.88 | EGFR (0.44) | JAK3PTK2JAK2POLBMAPT | |
| SCHEMBL31379898 | 0.87 | SYK (0.44) | JAK3PTK2JAK2IDH2SYK | |
| SCHEMBL31379880 | 0.86 | JAK2 (0.56) | JAK3PTK2JAK2GPR119 | |
| SCHEMBL31379913 | 0.85 | GPR119 (0.51) | JAK3PTK2JAK2GPR119 | |
| SCHEMBL31379921 | 0.84 | ALDH1A1 (0.48) | JAK3PTK2JAK2 | |
| SCHEMBL31379895 | 0.83 | GRM1 (0.48) | JAK3PTK2JAK2IDH2 | |
| SCHEMBL31379924 | 0.82 | JAK2 (0.46) | JAK3PTK2JAK2SYKGPR119 | |
| SCHEMBL31379884 | 0.81 | ALDH1A1 (0.47) | JAK3PTK2JAK2MAPT | |
| SCHEMBL31379910 | 0.81 | JAK3 (0.51) | JAK3PTK2JAK2GPR119 | |
| SCHEMBL31379866 | 0.78 | IDH2 (0.56) | POLBMAPTIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025027560-A1 | NEW RHOJ/CDC42 INHIBITORS DEVELOPED FOR THE TREATMENT OF CANCER, BENIGN TUMORS, RETINAL DISORDERS, VASCULAR DISORDERS, AND CARDIOMYOPATHIES | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-02-06 | — | — | WO | disclosed |