Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAC1 | P63000 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388179 | 1.00 | HTR1A (0.49) | HTR1AHTR6MAPTRAC1CCR4 | |
| SCHEMBL3388954 | 0.89 | HTR1D (0.53) | HTR1AMAPTRAC1CCR4HTR2A | |
| SCHEMBL13019374 | 0.88 | HTR2A (0.51) | HTR1AHTR6MAPTHTR2AUSP2 | |
| SCHEMBL3389960 | 0.82 | HTR1D (0.53) | HTR1AMAPTRAC1CCR4HTR2A | |
| SCHEMBL3390345 | 0.76 | HTR1D (0.55) | HTR1AMAPTHTR2AMEN1KMT2A | |
| SCHEMBL3392632 | 0.72 | RAC1 (0.58) | MAPTRAC1CCR4CACNA2D1 | |
| SCHEMBL29839992 | 0.71 | HTR2A (0.50) | HTR1AHTR6HRH3HTR2AMEN1 | |
| SCHEMBL21996622 | 0.70 | PAK4 (0.57) | HTR1AHTR6MAPTHTR2AUSP2 | |
| SCHEMBL29839953 | 0.70 | PAK4 (0.57) | HTR1AHTR6MAPTHTR2AUSP2 | |
| Diethyltryptamine SCHEMBL517713 | 0.69 | HTR1A (1.00) | HTR1AHTR6MAPTHRH3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025027560-A1 | NEW RHOJ/CDC42 INHIBITORS DEVELOPED FOR THE TREATMENT OF CANCER, BENIGN TUMORS, RETINAL DISORDERS, VASCULAR DISORDERS, AND CARDIOMYOPATHIES | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-02-06 | — | — | WO | disclosed |