Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | HCK | P08631 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14826051 | 0.91 | PIK3C3 (0.51) | PIK3C3DYRK1AMEN1KMT2AABL1 | |
| SCHEMBL30186393 | 0.83 | HSD17B2 (0.47) | PIK3C3ESR1ESR2PIK3CAHSD17B1 | |
| SCHEMBL3321465 | 0.82 | FLT3 (0.48) | PIK3C3DYRK1AABL1PIK3CDEGFR | |
| SCHEMBL21364619 | 0.82 | PIK3C3 (0.46) | PIK3C3DYRK1AALOX5ABL1PIK3CD | |
| SCHEMBL5252715 | 0.81 | KDR (0.50) | PIK3C3DYRK1AMEN1KMT2AABL1 | |
| SCHEMBL3196029 | 0.81 | DYRK1A (0.58) | PIK3C3DYRK1AABL1PIK3CDEGFR | |
| SCHEMBL5248144 | 0.79 | PIK3C3 (0.47) | PIK3C3DYRK1AMEN1KMT2AABL1 | |
| SCHEMBL601353 | 0.79 | PIK3C3 (0.41) | PIK3C3DYRK1AMEN1KMT2AABL1 | |
| SCHEMBL29303281 | 0.78 | PIK3CD (0.44) | PIK3C3DYRK1AABL1PIK3CDEGFR | |
| Hydrochloric Acid SCHEMBL26967225 | 0.77 | PIK3C3 (0.40) | PIK3C3DYRK1AMEN1KMT2AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | UNIV DE VELENCIA (ES) | 2026-03-12 | — | — | US | claimed |
| WO-2025003545-A1 | DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY | UNIVERSITAT DE VALÈNCIA (ES) | 2025-01-02 | — | — | WO | claimed |
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | UNIV DE VELENCIA (ES) | 2026-03-12 | — | — | US | disclosed |
| WO-2025003545-A1 | DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY | UNIVERSITAT DE VALÈNCIA (ES) | 2025-01-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | IL1A, IL6, IL1B | PIK3C3 3057/4885DYRK1A 4627/4885ESR1 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.