SCHEMBL31381002

SCHEMBL31381002

CSc1ncc(Br)c(/N=C/N(C)C)n1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
HBB P68871 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALOX15 P16050 1/20 0.33
RECQL P46063 1/20 0.33
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31466856 0.83 FGFR1 (0.34) MEN1KMT2AMAPTL3MBTL1MAPK1
SCHEMBL16286354 0.81 ALOX15 (0.33) MEN1KMT2AMAPTL3MBTL1ALOX15
SCHEMBL12515514 0.81 ALOX15 (0.33) MEN1KMT2AMAPTL3MBTL1ALOX15
SCHEMBL2035429 0.81 ALOX15 (0.33) MEN1KMT2AMAPTL3MBTL1ALOX15
SCHEMBL23030180 0.79 CYP1A2 (0.39) MEN1KMT2AMAPTL3MBTL1MAPK1
SCHEMBL29882745 0.79 MAPT (0.36) MEN1KMT2AMAPTL3MBTL1MAPK1
SCHEMBL23030203 0.79 MAPT (0.36) MEN1KMT2AMAPTL3MBTL1MAPK1
SCHEMBL29882667 0.79 CYP1A2 (0.39) MEN1KMT2AMAPTL3MBTL1MAPK1
SCHEMBL24340010 0.72 KDM4E (0.33) L3MBTL1MAPK1HTTHSD17B10ALOX15
SCHEMBL32662109 0.70 HSD17B10 (0.37) MEN1KMT2AMAPTL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026903-A1 IMIDAZO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER BAYER AKTIENGESELLSCHAFT (DE) 2025-02-06 WO disclosed