Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MPO | P05164 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931918 | 1.00 | KDM4E (0.66) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL28858309 | 0.89 | MAPT (0.58) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL22357157 | 0.86 | KDM4E (0.69) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL29367542 | 0.86 | KDM4E (0.69) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL1833783 | 0.86 | KDM4E (0.69) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL8244909 | 0.86 | KDM4E (0.69) | KDM4EMAPTMEN1KMT2ALMNA | |
| Dl-Tryptophan SCHEMBL8059982 | 0.85 | KDM4E (0.82) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL31436164 | 0.85 | KDM4E (0.69) | KDM4EMAPTMEN1KMT2ALMNA | |
| Tryptophan SCHEMBL6688035 | 0.85 | KDM4E (0.82) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL1132857 | 0.85 | KDM4E (0.69) | KDM4EMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453724-B | Sulfonylmaleimide-based linkers and corresponding conjugates | 皮埃尔法布雷医药公司 | 2025-02-25 | — | — | CN | disclosed |