Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MPO | P05164 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436164 | 1.00 | KDM4E (0.69) | KDM4EMAPTMEN1LMNAMPO | |
| Tryptophan SCHEMBL6688035 | 0.90 | KDM4E (0.82) | KDM4EMAPTMEN1LMNAMPO | |
| Dl-Tryptophan SCHEMBL27153460 | 0.90 | KDM4E (0.82) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL1132348 | 0.90 | KDM4E (0.65) | KDM4EMAPTMEN1LMNAMPO | |
| Dl-Tryptophan SCHEMBL8059982 | 0.90 | KDM4E (0.82) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL11768547 | 0.87 | KDM4E (0.72) | KDM4EMAPTMEN1LMNAMPO | |
| Tryptophan SCHEMBL1487572 | 0.86 | KDM4E (0.76) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL3401965 | 0.86 | KDM4E (0.64) | KDM4EMAPTMEN1LMNAMPO | |
| Dl-Tryptophan SCHEMBL27865136 | 0.86 | KDM4E (0.76) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL3036060 | 0.86 | KMT2A (0.76) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408032-B1 | Coupling product between tryptamine and an alpha-amino acid and its use in the field of neuro-cosmetics | EXSYMOL SA (MC) | 2011-02-16 | — | — | EP | claimed |
| US-7094796-B2 | Coupling product between tryptamine and an alpha-amino acid, process for its preparation as well as its application in the neurocosmetic field | EXSYMOL S.A.M. (MC) | 2006-08-22 | — | — | US | claimed |
| US-20040110814-A1 | Coupling product between tryptamine and an alpha-amino acid, process for its preparation as well as its application in the neurocosmetic field | EXSYLMOL S.A.M. | 2004-06-10 | — | — | US | claimed |
| EP-1408032-B1 | Coupling product between tryptamine and an alpha-amino acid and its use in the field of neuro-cosmetics | EXSYMOL SA (MC) | 2011-02-16 | — | — | EP | disclosed |
| US-7094796-B2 | Coupling product between tryptamine and an alpha-amino acid, process for its preparation as well as its application in the neurocosmetic field | EXSYMOL S.A.M. (MC) | 2006-08-22 | — | — | US | disclosed |
| US-20040110814-A1 | Coupling product between tryptamine and an alpha-amino acid, process for its preparation as well as its application in the neurocosmetic field | EXSYLMOL S.A.M. | 2004-06-10 | — | — | US | disclosed |
| EP-1408032-A2 | Coupling product between tryptamine and an alpha-amino acid and its use in the field of neuro-cosmetics | EXSYMOL S.A.M. (MC) | 2004-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110814-A1 | Coupling product between tryptamine and an alpha-amino acid, process for its preparation as well as its application in the neurocosmetic field | TPH1, IDO1, KYNU | KDM4E 4594/4885MAPT 680/4885MEN1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.