SCHEMBL931918

SCHEMBL931918

NC(CCC(=O)O)Cc1c[nH]c2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.66
▸ MAPT P10636 3/20 0.66
▸ MEN1 O00255 2/20 0.66
▸ KMT2A Q03164 2/20 0.66
▸ LMNA P02545 1/20 0.66
▸ MPO P05164 1/20 0.66
▸ TSHR P16473 1/20 0.66
▸ BLM P54132 1/20 0.66
▸ PMP22 Q01453 1/20 0.66
▸ HIF1A Q16665 1/20 0.66
▸ HTR2A P28223 2/20 0.61
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ POLB P06746 2/20 0.58
▸ APAF1 O14727 1/20 0.58
▸ RECQL P46063 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ ADRB1 P08588 1/20 0.56
▸ HTR1A P08908 1/20 0.56
▸ ADRA2A P08913 1/20 0.56
▸ SLC6A2 P23975 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31383386 1.00 KDM4E (0.66) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL28858309 0.89 MAPT (0.58) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL22357157 0.86 KDM4E (0.69) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL29367542 0.86 KDM4E (0.69) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL1833783 0.86 KDM4E (0.69) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL8244909 0.86 KDM4E (0.69) KDM4EMAPTMEN1KMT2ALMNA
Dl-Tryptophan SCHEMBL8059982 0.85 KDM4E (0.82) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL31436164 0.85 KDM4E (0.69) KDM4EMAPTMEN1KMT2ALMNA
Tryptophan SCHEMBL6688035 0.85 KDM4E (0.82) KDM4EMAPTMEN1KMT2ALMNA
SCHEMBL1132857 0.85 KDM4E (0.69) KDM4EMAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3697208-B1 HIGH-FIDELITY LONG-TERM STORAGE OF BIOLOGICAL MATERIAL CENTRE NAT RECH SCIENT (FR) 2026-04-22 — — EP disclosed
EP-4687443-A1 METHOD FOR FUNCTIONALISING A SOLID SUBSTRATE WITH A PEPTIDE CONJUGATE Genepep (FR) 2026-02-11 — — EP disclosed
US-12250944-B2 High-fidelity long-term storage of biological material CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2025-03-18 — — US disclosed
US-20240350657-A1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES PIERRE FABRE MEDICAMENT (FR) 2024-10-24 — — US disclosed
WO-2024208878-A1 METHOD FOR FUNCTIONALISING A SOLID SUBSTRATE WITH A PEPTIDE CONJUGATE GENEPEP (FR) 2024-10-10 — — WO disclosed
EP-3856258-B1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES PF MEDICAMENT (FR) 2024-07-31 — — EP disclosed
US-12011485-B2 Sulfomaleimide-based linkers and corresponding conjugates PIERRE FABRE MEDICAMENT (FR) 2024-06-18 — — US disclosed
US-20230414702-A1 COMPOUNDS AND PHARMACEUTICAL USE THEREOF IN THE TREATMENT OF CANCER PEPKON SAS (FR) 2023-12-28 — — US disclosed
US-11759496-B2 Compounds and pharmaceutical use thereof in the treatment of cancer Karoyan, Philippe (FR) 2023-09-19 — — US disclosed
US-11383008-B2 Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-07-12 — — US disclosed
EP-2505210-A1 Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanionic polypeptide for the treatment of aids INSTITUT PASTEUR (FR) 2012-10-03 — — EP disclosed
WO-2012085221-A1 DERIVATIVES OF GLYCO-CF2-SERINE AND GLYCO-CF2-THREONINE TFCHEM (FR) 2012-06-28 — — WO disclosed
EP-2448956-A1 SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS Centre National De La Recherche Scientifique CNRS (FR) 2012-05-09 — — EP disclosed
US-20120108748-A1 SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-05-03 — — US disclosed
US-20110152464-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT UNIVERSITE DE MONTPELLIER I (FR) 2011-06-23 — — US disclosed
EP-2321277-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT Centre National de la Recherche Scientifique - CNRS (FR) 2011-05-18 — — EP disclosed
WO-2011000848-A1 SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-01-06 — — WO disclosed
EP-2270025-A1 Solid phase peptide synthesis of peptide alcohols Centre National pour la Recherche Scientifique (CNRS) (FR) 2011-01-05 — — EP disclosed
WO-2010023295-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-03-04 — — WO disclosed
US-20080249030-A1 Age Inhibitors CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-10-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108748-A1 SOLID PHASE PEPTIDE SYNTHESIS OF PEPTIDE ALCOHOLS VIP, ERG28, PSAP KDM4E 3122/4885MAPT 2095/4885MEN1 1770/4885
US-12011485-B2 Sulfomaleimide-based linkers and corresponding conjugates CSGALNACT1, CD44, IGLV6-57 KDM4E 423/4885MAPT 989/4885MEN1 2202/4885
US-20110152464-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT PRRC2C, VIP, PRRC2A KDM4E 4692/4885MAPT 1636/4885MEN1 3165/4885
US-11383008-B2 Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry CLASP1, MACF1, MICA KDM4E 1086/4885MAPT 3224/4885MEN1 2423/4885
US-11759496-B2 Compounds and pharmaceutical use thereof in the treatment of cancer VIP, RNASE1, ABCB11 KDM4E 4000/4885MAPT 4394/4885MEN1 767/4885
US-20230414702-A1 COMPOUNDS AND PHARMACEUTICAL USE THEREOF IN THE TREATMENT OF CANCER VIP, RNASE1, ABCB11 KDM4E 4000/4885MAPT 4394/4885MEN1 767/4885
US-20240350657-A1 SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES STS, SULT1E1, CD44 KDM4E 617/4885MAPT 1344/4885MEN1 1302/4885
US-20080249030-A1 Age Inhibitors CFH, XPA, XPNPEP1 KDM4E 984/4885MAPT 3229/4885MEN1 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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