Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL313595 | 1.00 | DNM1 (0.52) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL6289482 | 1.00 | DNM1 (0.52) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL727878 | 1.00 | DNM1 (0.52) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL27904226 | 1.00 | DNM1 (0.52) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL441666 | 0.98 | DNM1 (0.50) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL3282068 | 0.98 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| SCHEMBL240163 | 0.98 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| SCHEMBL4313259 | 0.98 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| SCHEMBL238533 | 0.98 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| SCHEMBL239715 | 0.98 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160017-B | Preparation method of high-strength open-cell zirconia foam ceramic | 中国科学院上海硅酸盐研究所 | 2023-06-02 | — | — | CN | claimed |
| CN-115160017-A | Preparation method of high-strength open-cell zirconia foamed ceramic | 中国科学院上海硅酸盐研究所 | 2022-10-11 | — | — | CN | claimed |
| CN-111205093-A | Preparation method of ultra-light silicon nitride foamed ceramic | 中国科学院上海硅酸盐研究所 | 2020-05-29 | — | — | CN | claimed |
| EP-2411560-A1 | PROCESS FOR SINTERING NANOPARTICLES AT LOW TEMPERATURES | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2012-02-01 | — | — | EP | claimed |
| WO-2010109465-A1 | PROCESS FOR SINTERING NANOPARTICLES AT LOW TEMPERATURES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-09-30 | — | — | WO | claimed |
| WO-2001051767-A2 | ADDITION OF SOLIDS TO GENERATE VISCOSITY DOWNHOLE | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2001-07-19 | — | — | WO | claimed |
| US-20260042956-A1 | METHOD FOR SINGLE-STAGE TREATMENT OF SILICEOUS SUBTERRANEAN FORMATIONS | SCHLUMBERGER TECHNOLOGY CORPORATION | 2026-02-12 | — | — | US | disclosed |
| CN-119320274-A | Double-aperture distributed zirconia capillary core for loop heat pipe and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2025-01-17 | — | — | CN | disclosed |
| EP-2820093-B1 | INKS CONTAINING METAL PRECURSORS NANOPARTICLES | SINGAPORE ASAHI CHEMICAL & SOLDER IND PTE LTD (SG) | 2024-09-18 | — | — | EP | disclosed |
| US-12054626-B2 | Inks containing metal precursors nanoparticles | SINGAPORE ASAHI CHEMICAL & SOLDER IND. PTE. LTD (SG) | 2024-08-06 | — | — | US | disclosed |
| WO-2024026137-A1 | METHOD FOR SINGLE-STAGE TREATMENT OF SILICEOUS SUBTERRANEAN FORMATIONS | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-115160017-B | Preparation method of high-strength open-cell zirconia foam ceramic | 中国科学院上海硅酸盐研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-115160017-A | Preparation method of high-strength open-cell zirconia foamed ceramic | 中国科学院上海硅酸盐研究所 | 2022-10-11 | — | — | CN | disclosed |
| US-5979557-A | Methods for limiting the inflow of formation water and for stimulating subterranean formations | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| US-5964295-A | FOR REDUCING FLUID LOSS DURING FRACTURING OF A FORMATION | SCHLUMBERGER TECHNOLOGY CORPORATION, DOWELL DIVISION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0835983-A2 | Methods of fracturing subterranean formations | SOFITECH N.V. (BE) | 1998-04-15 | — | — | EP | disclosed |
| US-5551516-A | VISCOELASTIC SURFACTANT BASED AQUEOUS FLUID SYSTEMS USING A QUATERNARY AMMONIUM HALIDE THICKENER | DOWELL, A DIVISION OF SCHLUMBERGER TECHNOLOGY CORPORATION | 1996-09-03 | — | — | US | disclosed |
| EP-0142028-B1 | REVERSIBLE PHASE CHANGE COMPOSITION FOR STORING THERMAL ENERGY | THE DOW CHEMICAL COMPANY (US) | 1987-08-05 | — | — | EP | disclosed |
| US-4585572-A | CATIONIC SURFACTANT THICKENER | THE DOW CHEMICAL COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0142028-A1 | Reversible phase change composition for storing thermal energy | THE DOW CHEMICAL COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042956-A1 | METHOD FOR SINGLE-STAGE TREATMENT OF SILICEOUS SUBTERRANEAN FORMATIONS | YAP1, S100A10, FOXM1 | DNM1 925/4885ALDH1A1 4656/4885TP53 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.