Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863860 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPK1NPC1MTORACHE | |
| SCHEMBL14167631 | 0.83 | ALOX5 (0.35) | ALDH1A1MAPK1NPC1NQO2SMN1; SMN2 | |
| SCHEMBL15792855 | 0.83 | ALOX5 (0.35) | ALDH1A1MAPK1NPC1NQO2SMN1; SMN2 | |
| SCHEMBL16308833 | 0.83 | ALOX5 (0.35) | ALDH1A1MAPK1NPC1NQO2SMN1; SMN2 | |
| SCHEMBL21012154 | 0.78 | POLB (0.42) | ALDH1A1MAPK1NPC1MTORSMN1; SMN2 | |
| SCHEMBL675033 | 0.77 | AMY1A (0.43) | ALDH1A1NPC1NQO2SMN1; SMN2TP53 | |
| SCHEMBL11444758 | 0.77 | AMY1A (0.43) | ALDH1A1NPC1NQO2SMN1; SMN2TP53 | |
| SCHEMBL675032 | 0.77 | AMY1A (0.43) | ALDH1A1NPC1NQO2SMN1; SMN2TP53 | |
| SCHEMBL29444188 | 0.77 | AMY1A (0.43) | ALDH1A1NPC1NQO2SMN1; SMN2TP53 | |
| SCHEMBL29443124 | 0.77 | AMY1A (0.43) | ALDH1A1NPC1NQO2SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064802-A1 | INHIBITING HUMAN INTEGRIN α5β1 | MORPHIC THERAPEUTIC, INC. (US) | 2025-03-27 | — | — | WO | disclosed |