Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | TACR3 | P29371 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385143 | 0.89 | TACR3 (0.57) | ADORA2BADORA2ATACR3CYP2C9ROCK2 | |
| SCHEMBL31385144 | 0.86 | ROCK2 (0.55) | ADORA2BADORA2ATACR3CYP2C9ROCK2 | |
| SCHEMBL31385239 | 0.83 | TACR3 (0.51) | TACR3CYP2C9MAPK1ALDH1A1POLB | |
| SCHEMBL31385131 | 0.81 | MAOA (0.61) | TACR3CYP2C9CDK2KDM4EALDH1A1 | |
| SCHEMBL31385140 | 0.80 | GAA (0.55) | TACR3CYP2C9ALDH1A1POLBHTT | |
| SCHEMBL14094506 | 0.79 | TACR3 (0.64) | TACR3CYP2C9MAPK1ALDH1A1 | |
| SCHEMBL31385317 | 0.79 | TACR3 (0.59) | TACR3CYP2C9ALDH1A1POLBHTT | |
| SCHEMBL31385130 | 0.79 | PTGER4 (0.56) | TACR3ADORA3 | |
| SCHEMBL31385169 | 0.78 | ADORA2A (0.53) | ADORA2BADORA2ATACR3ADORA3CHRM4 | |
| SCHEMBL6222176 | 0.77 | KDM4E (0.58) | ADORA2BADORA2ACYP2C9NAMPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | disclosed |