Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385143 | 0.83 | TACR3 (0.57) | ADORA2AADORA2BTACR3 | |
| SCHEMBL31385144 | 0.81 | ROCK2 (0.55) | ADORA2AADORA2BPPARGTACR3 | |
| SCHEMBL31385239 | 0.80 | TACR3 (0.51) | ADORA3TACR3 | |
| SCHEMBL31385233 | 0.78 | ADORA2B (0.53) | ADORA2AADORA2BADORA3TACR3CHRM4 | |
| SCHEMBL14094521 | 0.78 | TACR3 (0.60) | ADORA2ATACR3 | |
| SCHEMBL6392481 | 0.78 | PARP1 (0.49) | ADORA2AADORA2BADORA3PARP1PARP3 | |
| SCHEMBL31385183 | 0.78 | ADORA2A (0.48) | ADORA2APPARGTACR3SSTR4 | |
| SCHEMBL31385131 | 0.78 | MAOA (0.61) | TACR3 | |
| SCHEMBL14094516 | 0.76 | TACR3 (0.75) | TACR3 | |
| SCHEMBL31385130 | 0.76 | PTGER4 (0.56) | ADORA3TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | disclosed |