Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 8/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26118030 | 0.76 | PRKCG (0.38) | DDB1CRBNTNKSOPRM1OPRK1 | |
| SCHEMBL31386158 | 0.72 | MAPT (0.34) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL26683865 | 0.71 | DDB1 (0.41) | DDB1CRBNTNKS | |
| SCHEMBL31385819 | 0.71 | DDB1 (0.41) | DDB1CRBNTNKSMAPT | |
| SCHEMBL31640433 | 0.69 | CRBN (0.44) | DDB1CRBNKCNH2 | |
| SCHEMBL31386218 | 0.69 | PRKCG (0.34) | DDB1CRBNOPRM1OPRK1OPRL1 | |
| SCHEMBL31386199 | 0.69 | OPRL1 (0.33) | OPRM1OPRK1OPRL1CCR2 | |
| SCHEMBL26118679 | 0.68 | PRKCG (0.44) | DDB1CRBNKCNH2 | |
| SCHEMBL29207781 | 0.67 | CRBN (0.46) | DDB1CRBNKCNH2 | |
| SCHEMBL28783591 | 0.67 | CCR3 (0.38) | TNKSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |