Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143288 | 0.92 | SOS1 (0.41) | KCNH2MGLLTNKSTSHRMAPK1 | |
| SCHEMBL29201758 | 0.91 | HTT (0.40) | ADRB2HTTMGLLHSD11B1 | |
| SCHEMBL23134613 | 0.91 | TSHR (0.40) | KCNH2MGLLHSD11B1TSHRKMT2A | |
| SCHEMBL30009715 | 0.90 | MGLL (0.38) | CCR3HRH1KCNH2MGLLHSD11B1 | |
| SCHEMBL23121762 | 0.90 | MGLL (0.38) | CCR3HRH1KCNH2MGLLHSD11B1 | |
| SCHEMBL29201711 | 0.89 | HTT (0.39) | ADRB2HTTMGLLHSD11B1HRH3 | |
| Hydrochloric Acid SCHEMBL23121946 | 0.89 | MGLL (0.37) | CCR3HRH1KCNH2MGLLHSD11B1 | |
| Hydrochloric Acid SCHEMBL30009282 | 0.89 | MGLL (0.37) | CCR3HRH1KCNH2MGLLHSD11B1 | |
| SCHEMBL29277059 | 0.89 | HSD11B1 (0.39) | CCR3MGLLHSD11B1TSHR | |
| SCHEMBL27117097 | 0.89 | KMT2A (0.46) | ADRB2HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641473-A | BRD9 bifunctional degradation agent and use method thereof | 诺华股份有限公司 | 2022-06-17 | — | — | CN | disclosed |