Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386146 | 0.79 | CHRM2 (0.40) | CHRM2CHRM1SMN1; SMN2GAAHRH2 | |
| SCHEMBL30376515 | 0.78 | SMN1; SMN2 (0.42) | CHRM2CHRM1SMN1; SMN2GAAHRH2 | |
| SCHEMBL30417231 | 0.78 | PTGDR2 (0.43) | PTGDR2SMN1; SMN2HRH2HRH1ALDH1A1 | |
| SCHEMBL31386252 | 0.77 | SMN1; SMN2 (0.40) | CHRM2CHRM1SMN1; SMN2GAAALOX12 | |
| SCHEMBL27599197 | 0.76 | L3MBTL1 (0.55) | PTGDR2CHRM2CHRM1SMN1; SMN2GAA | |
| SCHEMBL31386170 | 0.73 | PRKCG (0.48) | — | |
| SCHEMBL30015372 | 0.73 | CHRM2 (0.44) | CHRM2CHRM1SMN1; SMN2GAAHRH2 | |
| SCHEMBL3306747 | 0.72 | LMNA (0.45) | CHRM2CHRM1SMN1; SMN2GAAHRH2 | |
| SCHEMBL31385737 | 0.72 | CHRM2 (0.40) | CHRM2CHRM1SMN1; SMN2GAAHRH2 | |
| SCHEMBL30015386 | 0.72 | L3MBTL1 (0.43) | CHRM2CHRM1SMN1; SMN2GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |