Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015422 | 0.93 | EPHX1 (0.46) | EPHX1ALDH1A1CYP1A2CYP2D6NPSR1 | |
| SCHEMBL10585977 | 0.82 | NPSR1 (0.47) | ALDH1A1CYP1A2NPSR1NOS1PPARG | |
| SCHEMBL4454018 | 0.79 | ALDH1A1 (0.42) | EPHX1ALDH1A1NPSR1LMNAHTT | |
| SCHEMBL8718202 | 0.75 | MEN1 (0.42) | EPHX1ALDH1A1CYP1A2CYP2D6NPSR1 | |
| SCHEMBL12885483 | 0.72 | BCHE (0.42) | EPHX1NPSR1ACEBCHEACHE | |
| SCHEMBL12510871 | 0.72 | EPHX1 (0.44) | EPHX1ALDH1A1CYP1A2CYP2D6GAA | |
| SCHEMBL5014066 | 0.70 | GABRA1 (0.37) | LMNA | |
| SCHEMBL19193214 | 0.70 | EPHX1 (0.54) | EPHX1ACEBCHEACHE | |
| SCHEMBL1336531 | 0.69 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2D6LMNAHTT | |
| SCHEMBL25636455 | 0.68 | ACE (0.43) | CYP1A2CYP2D6HRH3ACECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139878-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008101806-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |