Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20854762 | 0.87 | DAO (0.42) | LMNASMN1; SMN2MAPT | |
| SCHEMBL9068187 | 0.82 | ALDH1A1 (0.35) | GABRA1GABRB2LMNAADRB2ADRB1 | |
| SCHEMBL10585977 | 0.79 | NPSR1 (0.47) | SMN1; SMN2TRPA1 | |
| SCHEMBL5015422 | 0.75 | EPHX1 (0.46) | SMN1; SMN2 | |
| SCHEMBL19571032 | 0.73 | GABRA1 (0.43) | GABRA1GABRB2SMN1; SMN2MAPT | |
| SCHEMBL24768177 | 0.71 | GABRA1 (0.47) | GABRA1GABRB2MAPTPKM | |
| SCHEMBL3138628 | 0.70 | EPHX1 (0.42) | LMNA | |
| SCHEMBL3125412 | 0.70 | — | — | |
| SCHEMBL8718202 | 0.69 | MEN1 (0.42) | LMNASMN1; SMN2MAPTPKMTRPA1 | |
| SCHEMBL19407827 | 0.69 | RIPK1 (0.41) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310944-B1 | BISOXETHYLSULFONYLMETHYL ANILINES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-13 | — | — | EP | claimed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |