SCHEMBL313870

SCHEMBL313870

C=Cc1ccccc1/C=C/c1ccccc1C=C

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
NFE2L2 Q16236 7/20 0.46
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRPA1 O75762 2/20 0.37
GSR P00390 1/20 0.34
FGF23 Q9GZV9 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CHAT P28329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395459 1.00 ALDH1A1 (0.55) ALDH1A1NFE2L2TSHRMEN1LMNA
SCHEMBL29405187 0.90 ALDH1A1 (0.63) ALDH1A1NFE2L2TSHRMEN1LMNA
SCHEMBL7638 0.90 ALDH1A1 (0.63) ALDH1A1NFE2L2TSHRMEN1LMNA
SCHEMBL473080 0.90 ALDH1A1 (0.63) ALDH1A1NFE2L2TSHRMEN1LMNA
SCHEMBL1304546 0.87 NFE2L2 (0.56) ALDH1A1NFE2L2TSHRMEN1KMT2A
SCHEMBL1304550 0.87 NFE2L2 (0.56) ALDH1A1NFE2L2TSHRMEN1KMT2A
Water SCHEMBL20379011 0.87 ALDH1A1 (0.60) ALDH1A1NFE2L2TSHRMEN1LMNA
SCHEMBL9562250 0.87 ALDH1A1 (0.60) ALDH1A1NFE2L2TSHRMEN1LMNA
SCHEMBL11016199 0.87 ALDH1A1 (0.60) ALDH1A1NFE2L2TSHRMEN1LMNA
SCHEMBL1176773 0.87 ALDH1A1 (0.60) ALDH1A1NFE2L2TSHRMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250052927-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-13 US claimed
WO-2025032504-A2 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-02-13 WO claimed
US-11986997-B2 Three-dimensional printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2024-05-21 US claimed
EP-3957692-B1 PRIMER COMPOSITION MARABU GMBH & CO KG (DE) 2024-05-15 EP claimed
US-20220088856-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-03-24 US claimed
EP-3957692-A1 PRIMER COMPOSITION Marabu GmbH & Co. KG (DE) 2022-02-23 EP claimed
US-20210402684-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-12-30 US claimed
WO-2020251532-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2020-12-17 WO claimed
US-10254646-B2 Composition sensitive to radiation in electromagnetic spectrum ranges for printing purposes, printing plate comprising said composition, use of said composition and image development process IBF INDUSTRIA BRASILEIRA DE FILMES S/A (BR) 2019-04-09 US claimed
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2019-01-17 US claimed
EP-1848763-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN Arkema France (FR) 2007-10-31 EP claimed
US-20070221884-A1 Liminescent Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-09-27 US claimed
EP-1769049-A2 LUMINESCENT SILICON OXIDE FLAKES Ciba Specialty Chemicals Holding Inc. (CH) 2007-04-04 EP claimed
WO-2006087241-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2006-08-24 WO claimed
WO-2006008239-A2 LUMINESCENT SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO claimed
EP-1469124-A1 Use of a composition for whitening recycled paper and board pulp De Donato, Fausto (IT) 2004-10-20 EP claimed
EP-0913444-B1 Adhesive compositions VANTICO AG (CH) 2003-07-09 EP claimed
EP-1047729-B1 COMPOSITION FOR BLEACHING MECHANICAL PULP DE DONATO FAUSTO (IT) 2003-01-08 EP claimed
EP-1047729-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION De Donato, Fausto (IT) 2000-11-02 EP claimed
WO-1999029779-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION DONATO FAUSTO DE (IT) 1999-06-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL HNRNPM, NPM1, HNRNPF ALDH1A1 677/4885NFE2L2 946/4885TSHR 4415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.