Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33952 | 0.93 | ALDH1A1 (0.56) | CES2CES1ALDH1A1NR4A1HPGD | |
| SCHEMBL374630 | 0.89 | ALDH1A1 (0.56) | CES2CES1ALDH1A1NR4A1HPGD | |
| SCHEMBL8346950 | 0.84 | CES2 (0.65) | CES2CES1NR4A1MAPTLMNA | |
| SCHEMBL33953 | 0.84 | CES2 (0.65) | CES2CES1NR4A1MAPTLMNA | |
| SCHEMBL9577479 | 0.83 | CYP19A1 (0.46) | CES2CES1ALDH1A1NR4A1HPGD | |
| SCHEMBL374631 | 0.81 | SMN1; SMN2 (0.55) | CES2CES1ALDH1A1HPGDRAB9A | |
| SCHEMBL4416667 | 0.78 | CES2 (0.62) | CES2CES1ALDH1A1HPGDMAPT | |
| SCHEMBL8768011 | 0.78 | SLC6A4 (0.53) | CES2CES1NR4A1 | |
| 4-Chloro-Benzoic Acid SCHEMBL6852257 | 0.78 | ALDH1A1 (0.73) | CES2CES1ALDH1A1NR4A1HPGD | |
| SCHEMBL8633789 | 0.77 | CYP1A2 (0.52) | CES2CES1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230300-A1 | INHIBITORS FOR INHIBITING TUMOR METASTASIS | Forschungsverbund Berlin E.V. (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016092069-A1 | INHIBITORS FOR INHIBITING TUMOR METASTASIS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2016-06-16 | — | — | WO | disclosed |
| US-8314215-B2 | Mild chemically cleavable linker system | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-11-20 | — | — | US | disclosed |
| US-20100003735-A1 | Mild Chemically Cleavable Linker System | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-01-07 | — | — | US | disclosed |
| WO-2008094205-A2 | A MILD CHEMICALLY CLEAVABLE LINKER SYSTEM | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003735-A1 | Mild Chemically Cleavable Linker System | BTD, SPR, DDO | CES2 1529/4885CES1 828/4885ALDH1A1 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.