SCHEMBL313879

SCHEMBL313879

COC(=O)C(Cc1ccc(O)cc1)NC(=O)CO

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 1/20 0.64
MDM2 Q00987 1/20 0.64
LNPEP Q9UIQ6 1/20 0.61
NPSR1 Q6W5P4 2/20 0.59
KMT2A Q03164 1/20 0.59
TSHR P16473 1/20 0.57
ALDH1A1 P00352 2/20 0.57
NLRP3 Q96P20 1/20 0.56
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
HDAC1 Q13547 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
KDR P35968 1/20 0.53
THRB P10828 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
HSD17B10 Q99714 1/20 0.51
LCK P06239 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4157633 0.88 MDM4 (0.64) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL13819236 0.88 MDM4 (0.64) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL11940462 0.88 MDM4 (0.64) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL25446628 0.88 MDM4 (0.64) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL28923202 0.88 MDM4 (0.64) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL25446553 0.88 MDM4 (0.64) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL314059 0.88 MDM4 (0.52) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL27827915 0.87 MDM4 (0.63) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL27909735 0.87 MDM4 (0.63) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL28913090 0.87 MDM4 (0.63) MDM4MDM2LNPEPNPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
EP-1948713-B1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2013-12-04 EP disclosed
US-20130317118-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-11-28 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8436201-B2 Functionalized diphenolics and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-05-07 US disclosed
US-8436201-B2 Functionalized diphenolics and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-05-07 US disclosed
US-7935843-B2 Functionalized diphenolics and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-05-03 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
EP-1948713-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM Bezwada Biomedical LLC (US) 2008-07-30 EP disclosed
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-14 US disclosed
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-14 US disclosed
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-14 US disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135355-A1 FUNCTIONALIZED DIPHENOLICS AND ABSORBABLE POLYMERS THEREFROM DDT, DHCR7, NOTUM MDM4 1769/4885MDM2 993/4885LNPEP 1851/4885
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 MDM4 3509/4885MDM2 1693/4885LNPEP 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.