SCHEMBL314059

SCHEMBL314059

COC(=O)COC(=O)C(Cc1ccc(O)cc1)NC(=O)CO

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 1/20 0.52
MDM2 Q00987 1/20 0.52
LNPEP Q9UIQ6 3/20 0.49
NPSR1 Q6W5P4 2/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
NLRP3 Q96P20 1/20 0.46
KDR P35968 1/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
ERAP2 Q6P179 2/20 0.42
ERAP1 Q9NZ08 1/20 0.42
BACE1 P56817 1/20 0.42
FOLH1 Q04609 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313879 0.88 MDM4 (0.64) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL315157 0.87 MEN1 (0.51) KMT2AALDH1A1HDAC1HDAC6
SCHEMBL313634 0.86 TACR1 (0.51) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL2619552 0.86 ALDH1A1 (0.42) MDM4MDM2KMT2AALDH1A1HDAC1
SCHEMBL313074 0.83 MDM4 (0.55) MDM4MDM2KMT2AALDH1A1TSHR
SCHEMBL12534524 0.82 ALDH1A1 (0.47) KMT2AALDH1A1HDAC1HDAC6
SCHEMBL27909735 0.81 MDM4 (0.63) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL313537 0.81 MEN1 (0.58) MDM4MDM2KMT2AALDH1A1HDAC1
SCHEMBL29648509 0.78 NPSR1 (0.63) MDM4MDM2LNPEPNPSR1KMT2A
SCHEMBL1991726 0.77 ACE (0.62) KMT2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
EP-1948713-B1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2013-12-04 EP disclosed
US-20130317118-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-11-28 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
EP-1948713-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM Bezwada Biomedical LLC (US) 2008-07-30 EP disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 MDM4 3509/4885MDM2 1693/4885LNPEP 23/4885
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 MDM4 3509/4885MDM2 1693/4885LNPEP 23/4885
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 MDM4 3509/4885MDM2 1693/4885LNPEP 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.