Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 19/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208501 | 0.88 | OPRK1 (0.42) | OPRK1PDK2PDK4 | |
| SCHEMBL31133273 | 0.78 | GAA (0.41) | OPRK1 | |
| SCHEMBL23214285 | 0.78 | GAA (0.41) | OPRK1 | |
| SCHEMBL19813985 | 0.77 | L3MBTL1 (0.41) | OPRK1PDK2PDK4 | |
| SCHEMBL23012453 | 0.77 | OPRK1 (0.41) | OPRK1 | |
| SCHEMBL21713467 | 0.76 | L3MBTL1 (0.40) | OPRK1PDK2PDK4 | |
| SCHEMBL31216665 | 0.76 | CA12 (0.49) | OPRK1PDK2PDK4 | |
| SCHEMBL19278157 | 0.74 | TSHR (0.41) | OPRK1PDK2PDK4 | |
| SCHEMBL22674555 | 0.74 | KDM4E (0.51) | — | |
| SCHEMBL2025343 | 0.74 | SOS1 (0.40) | OPRK1PDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341127-B | Aminopyrazine compounds as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2024-12-17 | — | — | CN | disclosed |