Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261067 | 0.79 | CYP2D6 (0.42) | TRPV4LRRK2CYP11B2ALDH1A1 | |
| SCHEMBL30718081 | 0.79 | CYP2D6 (0.42) | TRPV4LRRK2CYP11B2ALDH1A1 | |
| SCHEMBL31388140 | 0.78 | PGR (0.36) | TRPV4 | |
| SCHEMBL31388096 | 0.76 | LRRK2 (0.36) | LRRK2KDM4EALDH1A1 | |
| SCHEMBL31388106 | 0.73 | AR (0.40) | KDM4EUSP2ALDH1A1 | |
| SCHEMBL31388163 | 0.65 | GAA (0.46) | ALDH1A1 | |
| SCHEMBL31261074 | 0.65 | ALDH1A1 (0.44) | TRPV4CYP11B1CYP11B2KDM4EUSP2 | |
| SCHEMBL21535962 | 0.63 | TRPV4 (0.41) | TRPV4CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL20673118 | 0.63 | TRPV4 (0.42) | TRPV4CYP11B1CYP11B2KDM4EUSP2 | |
| SCHEMBL22166995 | 0.63 | TAAR1 (0.38) | KDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490500-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-02-21 | — | — | CN | disclosed |