SCHEMBL31388218

SCHEMBL31388218

CC(C)(C)OC(=O)N1CCC(OC(=O)C(C)(C)C(=O)c2ccccn2)CC1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 11/20 0.55
▸ RBP4 P02753 1/20 0.50
▸ USP30 Q70CQ3 1/20 0.46
▸ POLB P06746 1/20 0.44
▸ KDR P35968 1/20 0.43
▸ HRH3 Q9Y5N1 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13128801 0.81 RBP4 (0.61) GPR119RBP4USP30POLB
SCHEMBL13391117 0.80 GPR119 (0.60) GPR119USP30POLBKDRKDM4E
SCHEMBL406827 0.79 GPR119 (0.62) GPR119RBP4USP30POLBKDM4E
SCHEMBL1137790 0.78 GPR119 (0.57) GPR119USP30POLBKDRKDM4E
SCHEMBL13591117 0.77 GPR119 (0.60) GPR119USP30POLBKDR
SCHEMBL29749275 0.77 GPR119 (0.62) GPR119RBP4
SCHEMBL1087898 0.77 GPR119 (0.62) GPR119RBP4
SCHEMBL8063381 0.76 USP30 (0.68) GPR119USP30POLBKDR
SCHEMBL1088005 0.76 L3MBTL1 (0.69) GPR119RBP4POLBKDR
SCHEMBL3556075 0.76 CHRM2 (0.56) GPR119USP30POLBKDRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431227-A Azacarbene catalysis is coupled by decarboxylation of (a) 中国海洋大学 2025-02-14 — — CN disclosed
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