Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 8/20 | 1.00 |
| ▸ | KEAP1 | Q14145 | 1/20 | 1.00 |
| ▸ | NOS1 | P29475 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799525 | 1.00 | PSMB8 (1.00) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL539847 | 0.84 | PSMB8 (0.72) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL31389041 | 0.84 | PSMB8 (0.72) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL8701782 | 0.81 | PSMB8 (0.68) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL8697415 | 0.79 | PSMB8 (0.64) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL8698994 | 0.79 | PSMB8 (0.64) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL8701312 | 0.78 | PSMB8 (0.62) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL25338094 | 0.76 | PSMB8 (0.61) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL118671 | 0.76 | PSMB8 (1.00) | PSMB8KEAP1NOS1KDM4EGAA | |
| SCHEMBL244119 | 0.76 | NOS1 (1.00) | PSMB8KEAP1NOS1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119259277-A | Azacyclic sulfur application of ketone compound | 昆明理工大学 | 2025-01-07 | — | — | CN | disclosed |