Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389296 | 0.91 | ALOX15 (0.52) | ALOX15SMN1; SMN2POLBKDM4EALDH1A1 | |
| SCHEMBL31389237 | 0.88 | ALOX15 (0.64) | ALOX15SMN1; SMN2HTTPTGER1MCL1 | |
| SCHEMBL2908552 | 0.88 | ALOX15 (0.64) | ALOX15SMN1; SMN2HTTPTGER1MCL1 | |
| Hydrochloric Acid SCHEMBL28687342 | 0.87 | ALOX15 (0.62) | ALOX15SMN1; SMN2HTTPTGER1MCL1 | |
| SCHEMBL31389259 | 0.86 | ALOX15 (0.58) | ALOX15RXRAMCL1ADAM17 | |
| SCHEMBL31389239 | 0.85 | ALOX15 (0.57) | ALOX15SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL31389261 | 0.85 | ALOX15 (0.57) | ALOX15SMN1; SMN2POLBRAB9AMAPT | |
| SCHEMBL31389294 | 0.85 | ALOX15 (0.57) | ALOX15MAPTLMNARXRAPTGER1 | |
| SCHEMBL31389232 | 0.84 | ALOX15 (0.56) | ALOX15RAB9ARXRAPTGER1ADAM17 | |
| SCHEMBL31425607 | 0.81 | AGTR1 (0.49) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |