Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389266 | 0.92 | ALOX15 (0.55) | ALOX15MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL31389252 | 0.91 | ALOX15 (0.65) | ALOX15MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31389256 | 0.89 | ALOX15 (0.50) | ALOX15MAPTTDP1ADAM17 | |
| SCHEMBL31389289 | 0.88 | MAPT (0.58) | ALOX15MAPTLMNATDP1ADAM17 | |
| SCHEMBL31389265 | 0.88 | MAPT (0.50) | ALOX15MAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL31389236 | 0.88 | MAPT (0.58) | ALOX15MAPTKDM4ESMN1; SMN2HTT | |
| SCHEMBL31389290 | 0.86 | ALOX15 (0.47) | ALOX15MAPTTDP1ADAM17 | |
| SCHEMBL31389313 | 0.82 | ALOX15 (0.47) | ALOX15MAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL31389238 | 0.81 | ALOX15 (0.57) | ALOX15KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4144311 | 0.81 | LMNA (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |