Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389266 | 0.92 | ALOX15 (0.55) | MAPTLMNASTAT3HTTSMN1; SMN2 | |
| SCHEMBL31389256 | 0.89 | ALOX15 (0.50) | MAPTALOX15ADAM17TP53TDP1 | |
| SCHEMBL31389296 | 0.88 | ALOX15 (0.52) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL31389236 | 0.88 | MAPT (0.58) | MAPTLMNAHTTSMN1; SMN2ALOX15 | |
| SCHEMBL31389289 | 0.88 | MAPT (0.58) | MAPTLMNAALOX15ADAM17TP53 | |
| SCHEMBL31389261 | 0.88 | ALOX15 (0.57) | MAPTLMNAPOLBSTAT3HTT | |
| SCHEMBL31389253 | 0.87 | SMN1; SMN2 (0.55) | MAPTLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL31389290 | 0.86 | ALOX15 (0.47) | MAPTALOX15L3MBTL1ADAM17TP53 | |
| SCHEMBL31389311 | 0.86 | GRM2 (0.58) | MAPTLMNAPOLBSTAT3HTT | |
| SCHEMBL31389238 | 0.81 | ALOX15 (0.57) | LMNASMN1; SMN2ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |