Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389232 | 0.90 | ALOX15 (0.56) | ALOX15ADAM17NR4A2RAB9AL3MBTL1 | |
| SCHEMBL31389266 | 0.90 | ALOX15 (0.55) | ALOX15ADAM17MAPTTP53TDP1 | |
| SCHEMBL31389283 | 0.88 | NR4A2 (0.46) | ALOX15ADAM17NR4A2RAB9AL3MBTL1 | |
| SCHEMBL31389256 | 0.87 | ALOX15 (0.50) | ALOX15ADAM17MAPTTP53TDP1 | |
| SCHEMBL31389310 | 0.87 | MEN1 (0.56) | RAB9AL3MBTL1 | |
| SCHEMBL31389265 | 0.86 | MAPT (0.50) | ALOX15ADAM17L3MBTL1MAPTTP53 | |
| SCHEMBL31389289 | 0.86 | MAPT (0.58) | ALOX15ADAM17MAPTTP53TDP1 | |
| SCHEMBL31389236 | 0.86 | MAPT (0.58) | ALOX15ADAM17L3MBTL1MAPTTP53 | |
| SCHEMBL31389296 | 0.86 | ALOX15 (0.52) | ALOX15ADAM17MAPTTDP1 | |
| SCHEMBL31389238 | 0.80 | ALOX15 (0.57) | ALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |