Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | DHODH | Q02127 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421301 | 0.86 | ALOX15 (0.61) | ALOX15DHODHP2RY12ALDH1A1HPGD | |
| SCHEMBL31389285 | 0.84 | ALOX15 (0.70) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL18528819 | 0.84 | ALOX15 (0.70) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9378807 | 0.81 | ALOX15 (0.66) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30421019 | 0.81 | ALOX15 (0.70) | ALOX15TLR8HTR3EHTR3BHTR3A | |
| SCHEMBL18528809 | 0.81 | ALOX15 (0.70) | ALOX15TLR8HTR3EHTR3BHTR3A | |
| SCHEMBL30438659 | 0.81 | ALOX15 (0.69) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20515870 | 0.81 | ALOX15 (0.69) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2908552 | 0.80 | ALOX15 (0.64) | ALOX15ELANEPTGER1MCL1 | |
| SCHEMBL31389237 | 0.80 | ALOX15 (0.64) | ALOX15ELANEPTGER1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |