Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 11/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389581 | 0.78 | CXCR2 (0.39) | CXCR2KDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL8005977 | 0.76 | PARP1 (0.50) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL12922693 | 0.76 | PARP1 (0.53) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL31389424 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL18226589 | 0.72 | MAPT (0.44) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL15160575 | 0.71 | HRH3 (0.37) | HTT | |
| SCHEMBL27118838 | 0.71 | HRH3 (0.37) | HTT | |
| SCHEMBL21260782 | 0.70 | CXCR2 (0.69) | CXCR2KDM4EALDH1A1TSHRCXCR4 | |
| SCHEMBL14942591 | 0.69 | PDK1 (0.48) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL3911820 | 0.69 | GAA (0.61) | CXCR2KDM4EALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |