Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 5/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14172831 | 0.83 | ADORA3 (0.42) | PDK1KDM4EADORA3ALDH1A1MAPT | |
| SCHEMBL31389555 | 0.82 | PDK1 (0.36) | PDK1KDM4EADORA3ALDH1A1MAPT | |
| SCHEMBL31389475 | 0.78 | CXCR2 (0.44) | CXCR2PDK1KDM4EALDH1A1MAPT | |
| SCHEMBL8005977 | 0.76 | PARP1 (0.50) | PDK1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12922693 | 0.76 | PARP1 (0.53) | PDK1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14172833 | 0.74 | ALDH1A1 (0.37) | PDK1KDM4EADORA3ALDH1A1MAPT | |
| SCHEMBL31389424 | 0.73 | KDM4E (0.50) | PDK1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL14172835 | 0.72 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2429975 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL18723840 | 0.71 | P2RX7 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |