Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005977 | 0.79 | PARP1 (0.50) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL12922693 | 0.79 | PARP1 (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL14942591 | 0.77 | PDK1 (0.48) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL31389935 | 0.76 | PDK1 (0.47) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL31389475 | 0.73 | CXCR2 (0.44) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL31389784 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL31389581 | 0.73 | CXCR2 (0.39) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL31389554 | 0.73 | MAPT (0.55) | KDM4EALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL977531 | 0.71 | ADORA1 (0.52) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL15980352 | 0.71 | PDK1 (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |