Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389723 | 0.80 | PROKR1 (0.36) | HTR2CHSD11B1 | |
| SCHEMBL31389531 | 0.76 | TSHR (0.39) | CYP2D6CHRM1ADRA1A | |
| SCHEMBL31389523 | 0.76 | HTR1A (0.36) | HTR1AADRA1AKCNH2 | |
| SCHEMBL31389672 | 0.75 | HTR1A (0.38) | HTR1ASLC6A2SLC6A4 | |
| SCHEMBL31389893 | 0.75 | NR3C1 (0.33) | — | |
| SCHEMBL23391609 | 0.74 | HTR1A (0.56) | HTR2CADRA2AHTR1AUSP2CYP1A2 | |
| SCHEMBL23391610 | 0.74 | HTR1A (0.56) | HTR2CADRA2AHTR1AUSP2CYP1A2 | |
| SCHEMBL31389576 | 0.73 | SLC16A3 (0.31) | — | |
| SCHEMBL13573057 | 0.72 | SLC6A2 (0.31) | HTR2CSLC6A2SLC6A4 | |
| SCHEMBL3393951 | 0.71 | KDM1A (0.34) | HTR2CSLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |