Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389949 | 0.85 | MET (0.42) | METCYP11B1CYP11B2 | |
| SCHEMBL31389478 | 0.81 | CHRM2 (0.39) | CHRM2CHRM1METADRA2A | |
| SCHEMBL31389393 | 0.81 | MET (0.36) | MET | |
| SCHEMBL31389534 | 0.72 | DDB1 (0.44) | SCDDDB1CRBNKDM5ANPC1 | |
| SCHEMBL17404486 | 0.71 | DDB1 (0.53) | CHRM2CHRM1SCDDDB1CRBN | |
| SCHEMBL31389821 | 0.71 | MET (0.37) | CHRM2CHRM1METCHRM3KDM5A | |
| SCHEMBL31389870 | 0.71 | — | — | |
| SCHEMBL29303028 | 0.70 | DDB1 (0.46) | SCDDDB1CRBNKDM5ANPC1 | |
| SCHEMBL30821940 | 0.70 | DDB1 (0.46) | SCDDDB1CRBNKDM5ANPC1 | |
| SCHEMBL31389663 | 0.70 | SPR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |