SCHEMBL31389393

SCHEMBL31389393

CN(C)c1ccc2cnn(C3CC(O[Si](C)(C)C(C)(C)C)C3)c2c1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MET P08581 2/20 0.36
TERT O14746 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31389949 0.81 MET (0.42) MET
SCHEMBL31389659 0.81 CHRM2 (0.37) MET
SCHEMBL31389731 0.78 TERT (0.37) TERTAPP
SCHEMBL31389478 0.71 CHRM2 (0.39) MET
SCHEMBL26997380 0.69 HSD11B1 (0.43)
SCHEMBL22358033 0.69 HSD11B1 (0.43)
SCHEMBL29176182 0.67 RXRA (0.47)
SCHEMBL20116278 0.66 CHRM2 (0.43)
SCHEMBL31389870 0.66
SCHEMBL31389663 0.65 SPR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025043225-A2 DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 GENENTECH, INC. (US) 2025-02-27 WO disclosed