Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389990 | 0.85 | ACHE (0.44) | FAAHGAAMAPTPOLBBCL9 | |
| SCHEMBL25266732 | 0.84 | POLB (0.55) | ENPP2RAB9AGAAMAPTPOLB | |
| SCHEMBL25212614 | 0.84 | POLB (0.55) | ENPP2RAB9AGAAMAPTPOLB | |
| SCHEMBL31389980 | 0.80 | ENPP2 (0.40) | ENPP2GAAMAPTKMT2A | |
| SCHEMBL31389984 | 0.80 | ENPP2 (0.40) | ENPP2GAAMAPTKMT2A | |
| SCHEMBL31389778 | 0.78 | PTPN2 (0.38) | ENPP2RAB9AFAAHGAAMAPT | |
| SCHEMBL12654126 | 0.78 | POLB (0.48) | GAAMAPTPOLBBCL9CTNNB1 | |
| SCHEMBL30685930 | 0.78 | GAA (0.48) | GAAMAPTPOLBBCL9CTNNB1 | |
| SCHEMBL12653859 | 0.78 | POLB (0.48) | GAAMAPTPOLBBCL9CTNNB1 | |
| SCHEMBL29716145 | 0.78 | GAA (0.48) | GAAMAPTPOLBBCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |