Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192648 | 0.74 | GAA (0.67) | KMT2AMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL23250446 | 0.74 | CYP3A4 (0.34) | HDAC1HDAC6 | |
| SCHEMBL5450263 | 0.70 | GAA (0.46) | KMT2AMAPTGAAL3MBTL1CYP1A2 | |
| SCHEMBL13846512 | 0.69 | GAA (0.44) | KMT2AMAPTGAAL3MBTL1CYP1A2 | |
| SCHEMBL31389820 | 0.68 | ALDH1A1 (0.38) | MAPTL3MBTL1CYP1A2ALDH1A1HTT | |
| SCHEMBL16451221 | 0.68 | HDAC1 (0.33) | KMT2AHDAC1HDAC6 | |
| SCHEMBL18550697 | 0.67 | L3MBTL1 (0.40) | KMT2AMAPTGAAL3MBTL1CYP1A2 | |
| SCHEMBL11918917 | 0.67 | ALDH1A1 (0.56) | KMT2AMAPTL3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL23813836 | 0.67 | HDAC1 (0.35) | CYP1A2HDAC1HDAC6 | |
| SCHEMBL10911325 | 0.67 | L3MBTL1 (0.52) | KMT2AMAPTGAAL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |