SCHEMBL3138995

SCHEMBL3138995

NS(=O)(=O)c1ccc(N2CCC(c3ccc(Cl)cc3)=N2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.64
▸ GLA P06280 3/20 0.64
▸ MAPT P10636 3/20 0.64
▸ TDP1 Q9NUW8 3/20 0.64
▸ S1PR2 O95136 2/20 0.64
▸ ALDH1A1 P00352 2/20 0.64
▸ LMNA P02545 2/20 0.64
▸ GAA P10253 2/20 0.64
▸ HPGD P15428 2/20 0.64
▸ ATM Q13315 2/20 0.64
▸ NPSR1 Q6W5P4 2/20 0.64
▸ S1PR4 O95977 1/20 0.64
▸ S1PR1 P21453 1/20 0.64
▸ ERAP1 Q9NZ08 1/20 0.64
▸ HTT P42858 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ CA1 P00915 8/20 0.55
▸ CA2 P00918 8/20 0.55
▸ PTGS2 P35354 6/20 0.55
▸ CA4 P22748 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11544710 0.89 MAPT (0.67) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL9283208 0.88 MAPT (0.69) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL554460 0.86 KDM4E (0.64) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL8981988 0.83 MAPT (0.60) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL11251929 0.83 MAPT (0.70) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL3139976 0.81 ALDH1A1 (0.71) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL14393649 0.81 MAPT (0.58) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL4830373 0.80 ALDH1A1 (0.63) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL3133306 0.80 ALDH1A1 (0.60) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL11476192 0.80 MAPT (0.60) KDM4EGLAMAPTTDP1S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115524922-B Photosensitive resin composition 旭化成株式会社 2025-02-18 — — CN claimed
CN-115449261-B Preparation method of coffee flavor printing ink based on recovery of coffee bean waste 扬州市祥华新材料科技有限公司 2023-07-11 — — CN claimed
CN-115524922-A Photosensitive resin composition 旭化成株式会社 2022-12-27 — — CN claimed
CN-115449261-A Preparation method of coffee flavor printing ink based on coffee bean waste recovery 扬州市祥华新材料科技有限公司 2022-12-09 — — CN claimed
CN-114774904-A Aluminum alloy chromium-free passivation agent containing fluorescent agent and preparation method and use method thereof 安徽光铧帝业化学有限公司 2022-07-22 — — CN claimed
CN-107759715-A Epoxy acrylic resin that succinimide is modified and preparation method thereof, negative photo glue composition 苏州瑞红电子化学品有限公司 2018-03-06 — — CN claimed
CN-101120046-B Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE 2011-02-23 — — CN claimed
US-20080214706-A1 Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin ARKEMA FRANCE (FR) 2008-09-04 — — US claimed
EP-1848763-B1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2008-04-16 — — EP claimed
CN-101120046-A Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE (FR) 2008-02-06 — — CN claimed
EP-1848763-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN Arkema France (FR) 2007-10-31 — — EP claimed
WO-2006087241-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2006-08-24 — — WO claimed
US-12303582-B2 Composition for the treatment of nail fungus OYSTERSHELL NV (BE) 2025-05-20 — — US disclosed
CN-115524922-B Photosensitive resin composition 旭化成株式会社 2025-02-18 — — CN disclosed
CN-221804330-U Optical laminate, polarized lens, and ophthalmic wearing article 日本化药株式会社 2024-10-01 — — CN disclosed
CN-118510853-A Marking composition for application to a sporting projectile 格朗德塔奇有限责任公司 2024-08-16 — — CN disclosed
US-3985670-A Liquid regulated-foam detergent compositions HENKEL & CIE G.M.B.H. (DT) 1976-10-12 — — US disclosed
US-3962116-A COMPOSITIONS OF OPTICAL BRIGHTNESS AND ALUMINOSILICATES AND METHODS OF THEIR PRODUCTION HENKEL & CIE G.M.B.H. (DT) 1976-06-08 — — US disclosed
US-3943178-A WASHING AGENT HENKEL & CIE GMBH (DT) 1976-03-09 — — US disclosed
US-3931033-A ETHOXYLATED ALCOHOL, ALKALI METAL SOAP, SEQUESTERANT, SOLVENT, WATER HENKEL & CIE G.M.B.H. (DT) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12303582-B2 Composition for the treatment of nail fungus DPM1, PIK3C3, ETF1 KDM4E 1587/4885GLA 114/4885MAPT 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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