SCHEMBL554460

SCHEMBL554460

CS(=O)(=O)c1ccc(N2CCC(c3ccc(Cl)cc3)=N2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.64
▸ GLA P06280 3/20 0.64
▸ MAPT P10636 3/20 0.64
▸ TDP1 Q9NUW8 3/20 0.64
▸ S1PR2 O95136 2/20 0.64
▸ ALDH1A1 P00352 2/20 0.64
▸ LMNA P02545 2/20 0.64
▸ GAA P10253 2/20 0.64
▸ HPGD P15428 2/20 0.64
▸ ATM Q13315 2/20 0.64
▸ NPSR1 Q6W5P4 2/20 0.64
▸ S1PR4 O95977 1/20 0.64
▸ S1PR1 P21453 1/20 0.64
▸ ERAP1 Q9NZ08 1/20 0.64
▸ HTT P42858 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ PTGS2 P35354 13/20 0.55
▸ PTGS1 P23219 4/20 0.49
▸ MAOB P27338 2/20 0.49
▸ NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11544710 0.89 MAPT (0.67) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL9283208 0.88 MAPT (0.69) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL3138995 0.86 KDM4E (0.64) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL28167303 0.86 MAOB (0.63) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL9356013 0.86 MAPT (0.67) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL11251929 0.83 MAPT (0.70) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL8981988 0.83 MAPT (0.60) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL9319043 0.82 MAPT (0.59) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL12924136 0.81 MAOB (0.72) KDM4EGLAMAPTTDP1S1PR2
SCHEMBL3139976 0.81 ALDH1A1 (0.71) KDM4EGLAMAPTTDP1S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117247747-A Light-conversion packaging adhesive film and preparation method thereof 上海润势科技有限公司 2023-12-19 — — CN claimed
CN-115895108-A Waste PP recycled plastic for high-transparency injection molding product 上海睿聚环保科技有限公司 2023-04-04 — — CN claimed
CN-101120046-B Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE 2011-02-23 — — CN claimed
US-20090129053-A1 LIGHT-ENHANCED ELEMENT LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. (TW) 2009-05-21 — — US claimed
US-20080214706-A1 Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin ARKEMA FRANCE (FR) 2008-09-04 — — US claimed
EP-1848763-B1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2008-04-16 — — EP claimed
CN-101120046-A Molded article exhibiting multi-color effects, associated lighting device and resin ARKEMA FRANCE (FR) 2008-02-06 — — CN claimed
EP-1848763-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN Arkema France (FR) 2007-10-31 — — EP claimed
US-20070159062-A1 Light-enhanced element LUMINOSO PHOTOELECTRIC TECHNOLOGY CO. 2007-07-12 — — US claimed
WO-2006087241-A1 MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN ARKEMA FRANCE (FR) 2006-08-24 — — WO claimed
US-12303582-B2 Composition for the treatment of nail fungus OYSTERSHELL NV (BE) 2025-05-20 — — US disclosed
CN-115895108-B Waste PP regenerated plastic for high-transparency injection molding product 上海睿聚环保科技有限公司 2024-04-19 — — CN disclosed
CN-117247747-A Light-conversion packaging adhesive film and preparation method thereof 上海润势科技有限公司 2023-12-19 — — CN disclosed
CN-115895108-A Waste PP recycled plastic for high-transparency injection molding product 上海睿聚环保科技有限公司 2023-04-04 — — CN disclosed
US-20220306836-A1 PHOTOPERIODIC CONTROL OF PHYTOCHROME WITH MATERIALS Lleaf Pty Ltd (AU) 2022-09-29 — — US disclosed
WO-2003021041-A2 METHOD FOR INCREASING THE WHITENESS OF PAPER BY MEANS OF CATIONIC POLYELECTROLYTES BASF AKTIENGESELLSCHAFT (DE) 2003-03-13 — — WO disclosed
WO-2003016624-A1 METHOD FOR PRODUCTION OF COATED PAPER WITH EXTREME WHITENESS BASF AKTIENGESELLSCHAFT (DE) 2003-02-27 — — WO disclosed
EP-0003568-A1 Composition comprising optical brightening agents for use in the whitening of paper coating compositions BAYER AG (DE) 1979-08-22 — — EP disclosed
US-4094634-A Anionic and nonionic emulsified optical brightener suspension with a hydrotropic agent CIBA GEIGY AG (CH) 1978-06-13 — — US disclosed
US-4042320-A PRINTING, OPTICAL BRIGHTENERS CIBA-GEIGY AG (CH) 1977-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12303582-B2 Composition for the treatment of nail fungus DPM1, PIK3C3, ETF1 KDM4E 1587/4885GLA 114/4885MAPT 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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