Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255707 | 0.80 | ABCB1 (0.51) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL28668021 | 0.80 | ABCB1 (0.51) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL31389850 | 0.76 | KDM1A (0.50) | CHRNB2CHRNA4HTR2CHTR2BKDM1A | |
| SCHEMBL10994234 | 0.75 | ABCB1 (0.60) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL26836233 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL1334062 | 0.72 | HTR2A (0.45) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL1334060 | 0.72 | HTR2A (0.45) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL24685527 | 0.71 | ABCB1 (0.56) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL27569086 | 0.71 | ABCB1 (0.61) | CHRNB2CHRNA4HTR2CHTR2BABCB1 | |
| SCHEMBL31389702 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |