⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389884 | 0.73 | — | — | |
| SCHEMBL31389997 | 0.71 | CHRNB2 (0.44) | — | |
| SCHEMBL29867964 | 0.69 | — | — | |
| SCHEMBL31250365 | 0.68 | KDM4E (0.41) | — | |
| SCHEMBL25307309 | 0.68 | KDM4E (0.41) | — | |
| SCHEMBL28263444 | 0.66 | MKNK1 (0.43) | — | |
| SCHEMBL28262385 | 0.66 | MKNK1 (0.43) | — | |
| SCHEMBL25037223 | 0.65 | — | — | |
| SCHEMBL31389716 | 0.65 | P4HB (0.33) | — | |
| SCHEMBL29139742 | 0.64 | RIPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |