Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 13/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.38 |
| ▸ | LCK | P06239 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | SMAD2 | Q15796 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31390348 | 0.90 | RIPK2 (0.46) | DYRK1ATGFBR1RIPK2LCKKDR | |
| SCHEMBL31214345 | 0.75 | DYRK1A (0.72) | DYRK1ARIPK1PFKFB3TGFBR1APP | |
| SCHEMBL5440581 | 0.70 | DYRK1A (0.53) | DYRK1ARIPK1PFKFB3TGFBR1APP | |
| SCHEMBL2461409 | 0.68 | DYRK1A (0.50) | DYRK1ARIPK1PFKFB3TGFBR1APP | |
| SCHEMBL2460153 | 0.68 | RIPK2 (0.55) | DYRK1ARIPK1PFKFB3APPKDM4E | |
| SCHEMBL24365752 | 0.68 | NAMPT (0.35) | — | |
| SCHEMBL6032917 | 0.67 | DYRK1A (0.62) | DYRK1ARIPK1PFKFB3TGFBR1APP | |
| SCHEMBL23480164 | 0.67 | DYRK1A (0.57) | DYRK1ARIPK1PFKFB3TGFBR1APP | |
| SCHEMBL24155396 | 0.66 | DYRK1A (0.60) | DYRK1ARIPK1TGFBR1APPKDM4E | |
| SCHEMBL22130152 | 0.66 | DYRK1A (0.70) | DYRK1ARIPK1PFKFB3TGFBR1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176814-A | PRMT5 inhibitor and application thereof | 艾立康药业股份有限公司 | 2024-12-24 | — | — | CN | disclosed |