Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.55 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462260 | 0.87 | RIPK2 (0.61) | RIPK2RIPK3RIPK1PFKFB3NOTUM | |
| SCHEMBL15918180 | 0.79 | CYP4F2 (0.48) | RIPK2RIPK3PFKFB3CYP4F2CYP4A11 | |
| SCHEMBL31214345 | 0.78 | DYRK1A (0.72) | RIPK1PFKFB3DYRK1ANPC1RAB9A | |
| SCHEMBL2457852 | 0.74 | PFKFB3 (0.55) | RIPK1PFKFB3DYRK1ANPC1RAB9A | |
| SCHEMBL2463712 | 0.74 | NOTUM (0.47) | RIPK2RIPK3NOTUMPOLBPTPN11 | |
| SCHEMBL2458769 | 0.73 | RIPK1 (0.50) | RIPK1DYRK1APOLBCYP1A2CYP3A4 | |
| SCHEMBL2464313 | 0.72 | NPC1 (0.50) | DYRK1ANOTUMPOLBPTPN11HPGDS | |
| SCHEMBL2457178 | 0.71 | DYRK1A (0.54) | RIPK1PFKFB3DYRK1ANPC1RAB9A | |
| SCHEMBL2461409 | 0.71 | DYRK1A (0.50) | RIPK1PFKFB3DYRK1ACYP1A2CYP3A4 | |
| SCHEMBL16437088 | 0.71 | DYRK1A (0.50) | RIPK1DYRK1ANPC1RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | RIPK2 3574/4885RIPK3 3776/4885RIPK1 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.