Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.44 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31390961 | 0.92 | OPRK1 (0.44) | OPRK1DPP4NPSR1POLBTSHR | |
| SCHEMBL15527865 | 0.84 | OPRK1 (0.48) | OPRK1DPP4NPSR1POLBTSHR | |
| SCHEMBL18398582 | 0.84 | OPRK1 (0.48) | OPRK1DPP4NPSR1POLBTSHR | |
| SCHEMBL21512801 | 0.82 | OPRK1 (0.46) | OPRK1DPP4NPSR1POLBTSHR | |
| SCHEMBL21769766 | 0.78 | OPRK1 (0.44) | OPRK1DPP4NPSR1POLBTSHR | |
| SCHEMBL5864153 | 0.78 | OPRK1 (0.50) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL15527494 | 0.78 | OPRK1 (0.50) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL31213812 | 0.78 | L3MBTL1 (0.42) | NPSR1POLBTSHRMEN1NPC1 | |
| SCHEMBL10668140 | 0.77 | OPRK1 (0.49) | OPRK1NPSR1POLBTSHRHSD17B10 | |
| SCHEMBL18020441 | 0.76 | SMN1; SMN2 (0.46) | OPRK1NPSR1POLBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067457-A1 | HETEROCYCLIC FUSED RING COMPOUND, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-04-03 | — | — | WO | disclosed |