Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394045 | 0.89 | MAPK1 (0.40) | LPLLIPGMAPK1P2RX7 | |
| SCHEMBL31394354 | 0.82 | MAPK1 (0.36) | LPLLIPGMAPK1P2RX7 | |
| SCHEMBL1646761 | 0.81 | LPL (0.44) | LPLLIPGMAPK1P2RX7ROCK1 | |
| SCHEMBL4471407 | 0.79 | LPL (0.42) | LPLLIPGMAPK1P2RX7ROCK1 | |
| SCHEMBL31394839 | 0.78 | PGR (0.32) | LPLLIPGROCK1 | |
| SCHEMBL25395984 | 0.77 | LPL (0.41) | LPLLIPGMAPK1P2RX7ROCK1 | |
| SCHEMBL29097905 | 0.75 | PNMT (0.34) | — | |
| SCHEMBL15056617 | 0.74 | MAPK1 (0.34) | LPLLIPGMAPK1P2RX7ROCK1 | |
| SCHEMBL22898250 | 0.74 | MEN1 (0.42) | MAPK1P2RX7ROCK1JAK2BTK | |
| SCHEMBL30316100 | 0.74 | LPL (0.39) | LPLLIPGMAPK1P2RX7JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |